Small Molecule Drug Design

Small Molecule Drug Design

Welcome to our Medicinal Chemistry Laboratory at UC San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences! We specialize in the design and synthesis of small molecules as research tools or candidate therapeutics for a variety of human diseases.  Learn more

FEATURED IMAGE:

The structure of a brain-penetrant microtubule-stabilizing triazolopyrimidine (top structure) under development for the treatment of Alzheimer’s disease, docked within the vinca site of tubulin (PBD: 5NJH) in a region that is adjacent to the guanosine diphosphate (bottom structure).